Scientific Proceedings. 



25 



22 (165) 



The influence of gelatin upon the viscosity of the blood. 

 By RUSSELL BURTON-OPITZ. 



[From the Physiological Laboratory of Cohunbia University, at the 

 College of Physicians and Surgeons. ] 

 Solutions of gelatin (1000 : 50) were introduced intravenously 

 after the normal viscosity of the blood had been determined. It was 

 found that the injections resulted in a very prompt increase in the 

 viscosity. The following data may serve as examples : 



Specific Gravity. Viscosity. 

 Before Inj. After Inj. Before Inj. After Inj. 



I.O565 I-0543 836 772 



23 (166) 



The hemolytic effects of organ and tumor extracts. 



By RICHARD WEIL (by invitation). 



[From the Huntington Fund for Cancer Research of the General 

 Memorial Hospital, Loomis Laboratory, Cornell University 

 Medical College, New York City.] 



The object of the present investigation was to determine the 

 causes of, or factors contributing to, the secondary anemias of 

 malignant tumors. The material made use of was supplied by Dr. 

 Beebe, and consisted of sarcomata artificially implanted in dogs. 

 The method was to crush these tumors in a mortar, mix them with 

 ten times their weight of salt solution, and then stir mechanically 

 for several hours. The hemolytic effect of this extract was tested 

 on a 1 per cent, emulsion of the red cells of dogs. Preliminary 

 experiments were made with extracts of kidneys of dogs prepared 

 in the same fashion. It was found that the cause of the variability 

 in the hemolytic effect of organ extracts, which has been noted 

 by previous observers, is the varying admixture of blood. Kid- 

 neys prepared bloodlessly, by perfusion with salt solution, are 

 hemolytic only in very low dilution, and after a long latent interval. 

 Kidneys suffused with blood are as a rule very much more active ; 

 occasionally less so. The effects of blood have been analyzed by 

 the separate addition of serum, emulsions of white cells (from 

 artificial abscesses), and of red cells after washing, to the bloodless 



