34 Society for Experimental Biology and Medicine. 



Five similar experiments were performed. In three cases, 

 lesions of one or two anastomoses, and thrombosis of the vessel, 

 occurred two days, ten days and thirty-five days after the opera- 

 tion. However, the wall of the transplanted segment remained 

 apparently normal. In the fourth case, the transplanted segment, 

 extirpated and examined six days after the operation, appeared to 

 be normal and perfectly united to the ends of the aorta. On the 

 fifth animal, a laparotomy was performed forty-eight days after 

 the transplantation. It was found that the pulsations were normal 

 in the abdominal aorta and the segment of carotid. The location 

 of the anastomoses was marked by a slight hardening of the 

 arterial wall. No dilatation of the transplanted segment was ob- 

 served. The animal was kept alive and is now, seventy-eight 

 days after the operation, in excellent condition. The pulsations 

 of the femoral arteries remained normal. 



The experiments show merely that a segment of a dog carotid 

 which had been transplanted in a cat could act as artery for 

 seventy-eight days at least. 



28 (171) 



Transplantation of the kidney with implantation of the renal 

 vessels in the aorta and vena cava. 



By ALEXIS CARREL. 



[From the Rockefeller Institute for Medical Research^ 



The transplantation of the kidney with implantation of the 

 renal vessels in the aorta and vena cava consists of extirpating 

 from an animal a kidney with its vessels, together with a patch of 

 the aorta and vena cava ; also of transplanting the kidney into the 

 abdomen of another animal and suturing the edges of the patches to 

 the edges of suitable openings made in the walls of the aorta and 

 vena cava. By this patching method, the anastomoses are more 

 safely performed than by the other methods of anastomosis. If 

 the patch be large enough, occurrence of gangrene in the trans- 

 planted organ is practically impossible. With Guthrie, I used this 

 method mainly on cats and obtained excellent results from the 

 standpoint of restoration of the circulation. In dogs, on account 



