Scientific Proceedings. 



119 



dog 244 was again planted with tumor. Four plants were made 

 with positive results in three and tumors are growing at the present 

 time. The immunity which dog 244 possessed as a result of the 

 previous growth and regression of the tumors could not have 

 been very marked. The effect of this transfusion upon tumors of 

 dog 116 was negative, since they continued to grow until the 

 death of the animal in a cachetic condition four weeks later. 



II. Dog 125. Weight 13 kilos. Tumors were planted Dec. 

 6th. All plants grew and continued to increase in size until the day 

 of transfusion, March 20. On this day the dog was bled 500 c.c. 

 and immediately transfused with the same quantity of blood from 

 Dog 163. The latter animal had previously grown these tumors, 

 but they had completely regressed. Repeated implantations 

 failed to give tumor growth, and although the animal had the 

 mange and was in poor physical condition, he was used for the 

 donor in the transfusion. Following the bleeding and transfusion 

 the tumors of dog 125 became softer and began to regress. The 

 regression continues at the present date. One tumor has entirely 

 disappeared and the others have subsided. There remains about 

 one eighth of the tumor tissue present at the time of transfusion. 

 A metastasis in one of the inguinal lymph nodes has appeared 

 since the transfusion. Before the transfusion four plants were 

 made on the back. These have developed since the transfusion 

 and are now growing slowly. There is therefore in this animal 

 at the present time one set of tumors regressing and another set 

 slowly growing. 



III. Dog 133. Weight 17 kilos. Tumors planted Jan. 31st; 

 first growth noticed Feb. 13th, and continued active until day of 

 transfusion. March 20th, bled 600 c.c and transfused 1500 c.c. 

 from dog 289. The latter animal was ig 1 /, kilos in weight, in 

 very good physical condition and naturally immune to the tumor. 

 Following this transfusion, which was the largest and of the best 

 quality that any animal in this series received, the tumors of dog 

 133 began to regress immediately, and at the present time the 

 regression is complete. 



We merely wish to present the facts and do not care to indulge 

 in a discussion regarding immunity to tumors or the bearing 

 which these experiments have upon current theories. 



