9 8 



Scientific Proceedings (98). 



the upstroke to the dicrotic notch. The subjects were 20 normal 

 men, and 1,600 cycles were measured. A curve in which the 

 average duration of systole and of diastole were plotted in relation 

 to pulse gave a striking picture of the shortening of systole and 

 diastole by increasing heart rate. 



The great variation in the length ot systole and diastole which 

 may occur within a single minute was emphasized. Both are 

 affected by respiration, and diastole, at least, by vaso-motor in- 

 fluences. 



It can now be definitely stated that the changes in the length 

 of the systole and the diastole observed in succeeding cycles have 

 no constant relation to each other, and theretore are probably 

 brought about in different ways. 



The special object of this communication is to attract attention 

 to the great difference in the average length of systoles and dias- 

 toles caused by a change in the position of the human body. 

 It has been found that, in sitting the systoles average by pulse 

 rates from 50-95.9 per cent, longer than in standing, and in lying 

 down 17 per cent, longer than in standing. The diastoles are 

 also lengthened, but only to about one half as much as the systoles. 



The change in the length of the systoles caused by change of 

 position of body, although of course influenced markedly by the 

 pulse rate, is not due to the pulse rate alone, for the systole may 

 be lengthened when the pulse rate has undergone no change, or 

 when it is changed, the percentage change in systole may be much 

 greater than that of the pulse rate. 



58 (1433) 



The extraction of "fat-soluble vitamine" from green foods. 



By Thomas B. Osborne and Lafayette B. Mendel. 



[From the Laboratory of the Connecticut Agricultural Experiment 

 Station, and the Sheffield Laboratory of Physiological Chemistry 

 in Yale University, New Haven, Conn.] 



We have recently published experimental data to demonstrate 

 the occurrence of "fat-soluble vitamine" in certain foods. 1 Mc- 

 Collum, Simmonds and Pitz 2 have stated that "ether extraction 



1 Osborne and Mendel, J. Biol. Chem., 1919, XXXVII. 187. 



J McCollum, Simmonds and Pitz, Am. J. Physiol., 1916, XLI, 363. 



