104 



Scientific Proceedings (99). 



62 (1437) 



The disinfection of vitalized tissues and the healing of wounds 

 with chinosol and salt. 1 



By William C. Lusk (by invitation). 



[From the University and Bellevue Hospital Medical College, N. Y. 



City.\ 



The objective is to bring positive and convincing proofs of the 

 healing value of chinosol in combination with salt. 



Chinosol is oxyquinolin sulphate. Ik vitro, though a powerful 

 antiseptic, it is very little germicidal. A 2 per cent, solution did 

 not kill staphylococcus aureus in 24 hours. Its disinfectant action 

 on vitalized tissues is therefore probably due to the excitement by 

 it of physiological stimuli to bring nature's forces of resistance to 

 the fore. 



Salt was combined with chinosol by the writer through the 

 influence of the writings of Col. Sir Almroth E. Wright 2 relating 

 to salt in the treatment of wounds. 



Clinical experience. — Examples of cases treated with chinosol 

 and salt are as follows: Primary union in incised wounds, as for 

 instance a case of cut tendons of the wrist; cases of acute suppur- 

 ation, as one of cellulitis of the leg covering an area about the 

 size of one's hand, due to colon bacillus, with sloughing interior, 

 in which, with the use of a solution of 2 per cent, chinosol and 5 

 per cent, sodium chloride, the opposing surfaces of the abscess 

 cavity were almost completely united on the ninth day; the heal- 

 ing of a whitlow with bone involvement without destruction of 

 the tendons (function returning) and with union of the soft parts 

 to the area of exposed bone, the latter having taken place by the 

 tenth day, using a solution of 2 per cent, chinosol and 0.85 per 

 cent, sodium chloride; the filling with granulations in about 5 

 weeks' time, of a bone cavity about 7 inches in length in an ex- 

 panded lower portion of the shaft of a tibia, resulting from an 

 operation for osteomyelitis, the whole medullary portion of the 



1 A foreword to an uncompleted paper read before the N. Y. Surgical Society, 

 February 12 , 1919. 



2 Wright, A. E., Lancet, 1915, II, p. 1009; 1916, I, p. 1203; 1918, I, p. 831. 



