Addenda. 



In dispensing the tincture of chinosol according to the formula 

 here given, a heavy precipitate will form when the ingredients 

 are first mixed with the alcohol, which on standing for 24 to 36 

 hours with occasional shakings of the mixture, will almost entirely 

 dissolve. The precipitate consisting mostly of oxyquinolin, 

 should be allowed to dissolve and should not be filtered off. 

 When, in making up the tincture of chinosol, the chinosol and 

 sodium chloride were first dissolved in the requisite amount of 

 water needed to dilute the 95 per cent, alcohol down to 80 per 

 cent., and the alcohol then added to this solution, the final residue 

 after two or three days, was insignificant, which technic of making 

 up this tincture seems to be the best. It requires 9.5 c.c. of 

 water to be added to 45.5 c.c. of 95 per cent alcohol to make an 

 80 per cent, alcohol (U. S. Pharmacopeia), oj 84 minims of water 

 to 396 minims of 95 per cent, alcohol. 



