n6 



Scientific Proceedings (99). 



lates gave negative resorcin tests. This shows that chloroform 

 and volatile substances of the various organs will not respond to 

 the tests. 



Portions of brain, liver, kidney, lungs, stomach and intestine 

 to which small amounts of chloral had been added (100 to 200 

 mg.) were distilled with steam. In each case both the modified 

 resorcin test and the phloroglucin test responded strongly positive. 



64 (1439). 



Immunity results from toxin-antitoxin injections. 

 By William H. Park. 



[From the Department of Health of the City of New York.] 



It has already been reported that three injections of toxin- 

 antitoxin given to children susceptible to diphtheria produced in 

 about 90 per cent, sufficient antitoxin to give a negative Schick 

 test and that the remaining 10 per cent, could be immunized by 

 a second series of injections. Also that this immunity had lasted 

 for 2% years. 



It still remained to be determined whether this immunity would 

 continue unabated, and also whether it is possible to immunize 

 infants while immune from the antitoxin transmitted to them 

 through their mothers. Tests have just been completed on sev- 

 eral institutions in which 2>/4 years have elapsed since the toxin- 

 antitoxin injections. The immunity continues as well developed 

 as in 234 years. It is hoped therefore, that the acquired immunity 

 may persist possibly for life as in the case of natural immunity. 

 Our ability to immunize the infants with passive immunity is 

 being tested on a large scale, some 1800 infants having been in- 

 jected. Only fifty of these have reached a period for testing. 

 These show an immunity of 70 per cent, against an average im- 

 munity of those at the same age (8 months) not treated of 30 per 

 cent. It seems therefore, that a very fair success can be achieved 

 in young infants and that with greater knowledge it is possible to 

 hope for a complete success. Small children and infants in con- 

 tradistinction to adults show almost no local or general reaction to 

 the injections. 



