Gastric Response to Extragastric Irritation. 117 



65 (1440) 



Gastric response to extragastric irritation. 



By W. Howard Barber. 



[From the Department of Surgery, University and Bellevue Hospital 



Medical College.} 



Occasional experience with the contracting stomach in the 

 open surgical abdomen has been confirmed and enlarged by sim- 

 ilar experimental studies on the mammalian stomach. For this 

 purpose, a dog is narcotized with morphia and ether, and opened, 

 under surgical conditions, in the upper abdomen with the least 

 possible mechanical trauma. The stomach is exposed and watched 

 for contractions. If a typical animal, after the lapse of three 

 minutes, two waves of peristaltic contractions occur on the exposed 

 part of the stomach and follow each other at intervals of twenty 

 second's. With the stomach contracting in this manner, the 

 gallbladder is seized in a crushing clamp for a few moments and 

 released; similarly, the appendix or the duodenum may be clamped 

 and released. In the great proportion of instances, there is a 

 cessation of the stomach's motility for three minutes, more or 

 less, followed by hypermotility after clamping in this manner the 

 gallbladder, appendix, or duodenum. The experimental series is 

 as follows: 



Table Showing Relation of Gastric Motility to Extragastric Irritation. 

 Exp. No. Organ Irritated. Change in Gastric Motility. 



10. 



Duodenum 



. . .0 



II. 



Parietal Periton .... 



Inhibition 





Caecum (Appen) . . . 



. . . . Pylorospasm 





Gallbladder 



. . . . Pylorospasm 





Pylorus 



. . . .Retrostal. — Hypermotil. — Gastrospasm 



18. 



Gallbladder 



. . . .Hypermotil. 







0 



20. 





. . . . Gastrospasm — Pylorospasm 





Gallbladder 



. . . . Retrostal. 



22. 



Gallbladder 



. . . . Retrostal. 





Duodenum 



. . . .Hypermotil. 



32. 





. . . . Pylorospasm 





Gallbladder 



. . . .0 



33- 





. . . . Retrostal. — Pylorospasm 





Gallbladder 



. . . . Retrostal. — Hypermotil. 





Parietal Periton .... 



. . . . Inhibition 



