28 



Scientific Proceedings (ioi). 



15 (1475) 



Method and results of a study of the distribution of iodine be- 

 tween cells and colloid of thyroid glands. 



By Arthur L. Tatum (by invitation). 



[From the Laboratory of Physiological Chemistry and Pharmacology, 

 University of Chicago.] 



Method. — Use was made of the fact that from frozen sections, 

 as prepared for histological study of fresh unfixed tissues, the 

 colloid of the thyroid gland completely disappears out of the 

 acini when the sections are floated in physiological salt solution. 

 The sections were picked out by means of a needle, washed in 

 another solution of salt solution, dried at 105 0 C, weighed and 

 analysed for iodine by the technique of Kendall. The iodine 

 in the colloid portion was sometimes determined by evaporation 

 of the salt solution containing the colloid, and at other times 

 differentially by analysis of the whole dried gland. 



Results. — In a series of about thirty experiments on dogs' 

 thyroids the thyroid iodine was found in the majority of in- 

 stances to be wholly in the colloid as the cell portion was free 

 from iodine. In a smaller percentage of cases the cell mass gave 

 only qualitative tests for iodine, which at the present stage of 

 this investigation might be considered due to unopened small 

 acini. 



The physiological significance of these findings is being in- 

 vestigated. 



16 (1476) 



On the certain dietary factors to be considered in the treatment of 

 cases of hyperthyroidism. 



By Jacob Rosenbloom. 



[From the Laboratory of Dr. Jacob Rosenbloom, Pittsburgh, Pa.] 



The writer has obtained clinical evidence that in formulating 

 a diet for patients suffering from hyperthyroidism, two important 

 factors must be considered; first, the diet should contain the 

 minimum amount of protein and second, foods low in iodine 

 content should be selected. 



