Studies in the Absorption of Fats. 



9i 



A sample of jugular blood was taken from a dog of 14 kg. 

 weight at 12 45, and then 50 c.c. of olive oil were given by stomach 

 tube. Another jugular sample was taken at 3:45. At 4:45, the 

 dog was stunned, the abdomen was opened and samples of portal 

 and mesenteric blood taken. Then another sample of jugular 

 was taken. The analyses of these samples are given in the table 

 in gms. per 100 c.c. of blood. The cholesterol remains constant. 

 The administration of 50 c.c. of olive oil raised the phosphatides 

 36 per cent, and the fatty acids 49 per cent. There is no dif- 

 ference, within the limits of error of the method (5 per cent.), be- 

 tween the jugular, mesenteric and portal. The absorption in this 

 particular experiment was moderate. In another experiment, 

 the fatty acids were increased 90 per cent, and still there was no 

 difference between the portal and jugular. 



| Cholesterol. 



Phosphatides. 



Fatty Acids. 



Hemoglobin. 



12:45. Jugular before giving oil .. . 



.23 



.42 



.65 



125% 



3:45. Jugular 



.22 



•52 



•93 



123% 



4:45. Animal stunned, portal 



•23 



•57 



.98 



126% 



Mesenteric 



.22 



.56 



•97 



122% 



Jugular 



.23 



•58 



1.02 



125% 



To sum up the evidence then, we can safely say (1) that d'Erri- 

 co's findings cannot be accepted because of the methods employed, 

 and that they are not corroborated by our own data, (2) that in 

 the experiments in which tying-off of lymph vessels was done, 

 absorption may have been due to the lymph stasis, and (3) that 

 the data here presented preclude the assumption of any very 

 marked participation of the blood vessels in the absorption of 

 fat leaving open the question of absorption of small amounts 

 beyond the detection of the methods used. 



54 (1514) 



Studies in the diastatic activity of the blood and blood sugar 

 curves indicating a decreased carbohydrate 

 tolerance in hyperthyroidism. 

 By John A. Killian 



[From the Laboratory of Pathological Chemistry, New York Post 

 Graduate Medical School and Hospital.] 

 In studying the carbohydrate tolerance in hyperthyroidism 

 and other conditions, three methods have been employed, the 



