Scientific Proceedings (106). 



3. It is already in considerable use on the continent in approxi- 

 mately this (Bang, Czapek and most French investigators in the 

 field). 



The term "Lipin," introduced by Gies, although by derivation 

 equally suitable, is believed to be less desirable because of the 

 present practice among biochemists of making little or no distinc- 

 tion between — in and — ine (signifying the presence of nitrogen). 

 For example MacLean uses the term lipin to mean lipoid sub- 

 stances containing nitrogen. 



Very little originality can be claimed for the above classification 

 and the writer freely acknowledges the help obtained from a study 

 of earlier classifications, notably those of Bang, Leathes, Gies and 

 MacLean. At the same time it is believed to be an improvement 

 on preceding classifications in that it provides a definite chemical 

 and metabolic basis which has hitherto been lacking. 



76 (1536) 

 Sodium citrate and scurvy. 

 By Harold K. Faber. 



[From the Stanford Medical School, San Francisco, California.] 



An Italian child ten months old was brought to the Children's 

 Clinic, Stanford Medical School, in October, 1919, suffering from 

 severe scurvy. The child had been fed from birth on raw certified 

 milk to which had been added sodium citrate in the proportion of 

 one grain to each ounce of modified milk. 



A series of seventeen guinea pigs was fed on oats and milk. 

 In the case of nine of these guinea pigs sodium citrate was added 

 to the milk in the following proportions: 2 animals, 0.25 per cent.; 

 2 animals, 0.50 per cent.; 3 animals, I per cent.; 1 animal 1.3 per 

 cent.; 1 animal 2.0 per cent. The period of feeding in this series 

 was ten to forty-six days. Of the animals to which sodium citrate 

 was given all except one, to which 0.50 per cent, was given for 

 forty-six days, developed scurvy. Of the eight animals to which 

 milk and oats only were given two developed scurvy. These 

 control animals were observed for periods of forty to forty-six 

 days. The average milk intake was 39.1 c.c. of milk per day for 

 the control animals and 41.6 c.c. for the sodium citrate animals. 



