Reflex Gastric Hypermotility. 



155 



balanced and safe for distribution. Prepared as stated it retains 

 its balance eight months and possibly much longer and its practi- 

 cally full immunizing value at least a year. What slight deterior- 

 ation occurs takes place equally in the toxin and antitoxin and 

 therefore there is no danger of the mixture becoming toxic. 



Constitutional disturbances are frequent. They are usually 

 observed in adults, especially in those who give a pseudo Schick 

 reaction. These disturbances are mostly due to the bacillary 

 substances which are present in the diphtheria toxin. 



Methods for refining the mixture for the complete removal of 

 the bacillary substances have not been found. Considerable of 

 these reacting substances can be eliminated through the use of 

 ammonium sulphate, sodium chloride and alcohol. 



82 (1542) 



Further observations upon reflex gastric hypermotility. 



By W. Howard Barber and George D. Stewart 



[From the Department of Surgery, New York University and Bellevue 

 Hospital Medical College.] 



Increase in the force or rate or change in the direction of 

 gastric contractions have followed irritation of the gallbladder, 

 duodenum, or appendix, experimentally, and these motor changes 

 have been associated with pathological gallbladders, duodenums, 

 and appendices, clinically. 1 It may be assumed, subject to further 

 experimental proof, that these organs constitute three of the 

 possible foci of reflex gastric stimulation. Were the nerve paths 

 known along which these impulses travel, it might be possible to 

 explain these motor responses and group other possible causes of 

 gastric motor unrest. 



Other observations of abnormal reflex gastric activity in which 

 the pyloric and fundic parts functionate separately are the fol- 

 lowing : 



1. Prostalsis of the pars pylorica, alone, occurring in the course 

 of irritation of the above organs and after thoracic vagus section. 



2. Anastalsis of the pars pylorica, alone, associated with 

 traumatization of the gallbladder. 



1 Proceedings Soc. Exp. Biol, and Med., Vol. XVI., No. 7. 



