Elimination of Carbon Monoxide. 205 



carbon monoxide affinity ratio of all bloods examined fall between 

 1 : 254 and 1 : 378, and (2) these variations bear no relation to the 

 hemoglobin percentage of the blood nor to the age and condition 

 of the subject. 



Subject. 



Age. 



Sex, 



Condition. 



Hemoglo- 

 bin. 



Affinity at 

 20 0 C. 











Per cent. 





H. S 



59 



Male 



Pernicious anemia 



38 



1 : 310 



M. G 



27 



Female 



Pernicious anemia, recent 



60 



1 : 323 









transfusion 







W. F 



38 



Male 



Diabetes mellitus 



60 



1 : 310 



J- B 



28 





Pulmonary tuberculosis 



80 



1 : 286 



M. H 



3 



Female 



Broncho pneumonia 



80 



1 : 298 



H. C 



31 



Male 



Chronic endocarditis 



85 



1 : 323 



E. K 



12 





Lobar pneumonia 



85 



1 : 254 



M. M 



14 



Female 



Diphtheria (convalescent) 



85 



1 : 275 



M. B 



48 





Tumor of spinal cord 



85 



1 : 364 



F. B 



53 





Mucous colitis 



85 



1 : 323 



S. C 



8 





Tuberculosis of hip joint 



90 



1 : 275 



E. G 



30 



Male 



Diabetes mellitus 



100 



1 : 323 



F. W 



20 





Normal 



100 



1 : 286 



M. G. T 



30 







100 



1 :378 



R. M. W 



23 



Female 





100 



1 : 378 



A. L. P 



36 



Male 





105 



1 : 364 



Y. H 



46 







no 



1 : 275 



H. W. H 



28 



11 





no 



1 : 323 



no (1570) 



The elimination of carbon monoxide and a method of 

 acceleration. 



By Howard W. Haggard (by invitation). 



[From the Physiological Laboratory, Yale University Medical 



School.] 



Carbon monoxide combines with hemoglobin with an affinity 

 about 300 times as great as that of oxygen for hemoglobin. Blood 

 is deprived of its oxygen-carrying power by combining with CO 

 and the organism suffers from a corresponding degree of anoxemia. 

 The severity of the damage done to the victim is dependent upon 

 the degree of anoxemia and especially upon the duration. Evi- 

 dently the rate of elimination is extremely important. 



A study has been made of the normal rate of elimination in 

 dogs gassed to 60 to 80 per cent, saturation of the hemoglobin with 



