206 



Scientific Proceedings (108). 



CO. If the animals survived, the blood was practically free of 

 CO in from two to three hours. 



The curve so obtained was relatively flat for the first half of 

 the period of elimination. A dog with 80 per cent, of the hemo- 

 globin combined with CO, at the end of an hour still showed 60 to 

 70 per cent. During the remainder of the elimination period the 

 drop in the curve was rapid. 



It is evident that considerable damage may be wrought even 

 after the inhalation of CO has stopped. 



The elimination of CO was studied in animals inhaling oxygen, 

 carbon dioxide, and oxygen-carbon dioxide mixtures following 

 gassing. 



With the inhalation of oxygen the rapidity of elimination was 

 increased to approximately double. The curve of elimination of 

 CO from the blood still maintained its normal shape. Deaths 

 from respiratory failure still occurred. 



Inhalations of 6 per cent, carbon dioxide in air, increased 

 the pulmonary ventilation, and thus accelerated greatly the period 

 of elimination to one half or less of the normal. The curve of 

 CO-hemoglobin in the blood tended to approach more nearly a 

 straight line. 



Inhalations of oxygen containing 6 per cent, carbon dioxide 

 resulted in complete elimination of the CO from the blood in from 

 15 to 20 minutes. The curve obtained was a straight line. 



With the inhalations of carbon dioxide death from respiratory 

 failure was prevented. 



in (1571) 



The influence of oxygen in expelling C0 2 from the blood. 



By Yandell Henderson and H. W. Haggard (by invitation). 



[From the Physiological Laboratory, Yale University Medical 



School.] 



Considerable theoretical significance attaches to the interaction 

 of oxygen and C0 2 in blood. That variations of C0 2 tension 

 influence the capacity for oxygen is generally accepted. There 

 has not been, however, universal agreement among observers 



