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Scientific Proceedings (127) 



Comparative data showed hypertrophy of the adrenals. Xo. 

 lTs glands weighed 4.91 gms. (right) and 5.22 gms. (left) as 

 compared with 1.5-2 gms. in a normal sheep. 



Histological examination showed hyperemia and hemorrhage 

 in the adrenals, which may explain the drop. The pancreas was 

 normal. 



Pathological examination showed the immediate cause of 

 death apparently pulmonary oedema. All the fat of the body 

 showed myxoedema which did not give any fat reaction with 

 Herxheimer's stain. The entire extent of the aorta and the 

 pulmonary arteries, together with the larger branches, showed 

 calcified plaques in the media next to the intima. The intima 

 was normal. Sections of these did not give any fat or iron 

 reactions. In the heart there was myxoedema of the subepicar- 

 dial fat and scattered areas where the myocardium had apparently 

 reverted to an embryonic type with large nuclei and a large 

 amount of cytoplasm with longitudinal striations of the peri- 

 phery. There was also marked hydropericardium and hydro- 

 thorax. The kidneys showed congestion of the glomeruli and 

 an enormous amount of colloid in the Bowman capsules, in the 

 convoluted and collecting tubules. The adrenals showed marked 

 hyperemia and hemorrhage areas. There was a considerable 

 amount of cortical tissue out of proportion to the medullary tis- 

 sue. ( Hyperemia and hemorrhage of the adrenals have been 

 ascribed to toxemia). The pancreas seemed to contain a normal 

 number of islands of Langerhans. 



