Experimental Anemia 



297 



tion. This is controlled largely by using ear muffs to prevent 

 heat radiation. 



Other sources are excitement and movement on the part of 

 the animal. 



Conclusions. 



1. The blood pressure in the central artery of a rabbit's ear 

 under properly controlled conditions ranges from 75 to 90 mm. 

 of mercury. 



2. The figures are sufficiently consistent to allow experi- 

 mental study of the blood pressure. 



3. Excitation, exercise and any stimulation tending to di- 

 late the vessels locally increases the pressure above basal figures. 



4. Injection of adrenalin shows the typical rise. 



Abstracts of Communications. 

 Western New York Branch 

 Fifth meeting. 

 Syracuse, New York, February 17, 1923. 

 145 (2105) 



The production of experimental anemia with symmetrical 

 di-isopropyl-hydrazine hydrochloride and related 

 compounds. 



By MEYER BODANSKY and HENRY C. HARTMAN (by invitation). 



[From the University of Texas, School of Medicine, Galveston, 



Texas.] 



In its physiological behavior, phenylhydrazine differs very 

 markedly from hydrazine in that it is extremely destructive of 

 red corpuscles. This effect may perhaps be attributed to the 

 phenyl group in the phenylhydrazine molecule. That alkyl sub- 

 stitution products of hydrazine, such as symmetrical di-isopropyl- 

 hydrazine, 1 may produce a very pronounced anemia, is shown 

 by the data in the following table : 



i This compound was synthesized by H. L. Loehte in the laboratories of 

 J. R. Bailey and W. A. Noyes (J. Am. Chem. Soc, 1921, xliii, 2597). The 

 authors are indebted to Dr. Loehte for supplying them with this compound. 



