424 



Scientific Proceedings (132) 



alcohol has proved to be the best solvent for vitamine among the 

 solvents used. If, however, we stress not only the activity of the 

 extract, but also the quantiy of nitrogenous and other impurities 

 accompanying the extract (selecting the one that gives a mini- 

 mum of such impurities), then the best among the solvents is 

 acetone. 



Vitamines B and D tend to run parallel with one another, so 

 that, as a rule, the higher the content of vitamine B, the higher 

 in vitamine D is the extract apt to be. 



The co-ferment shows no definite relation to either vitamine 

 B or D. 



On the whole, the higher the nitrogen content of the extract, 

 the greater the percentage of total solids, and the greater the 

 activity of the extract. 



Using these solvents on rice polishings instead of on yeast, we 

 find that 60 per cent, alcohol is better than 70 per cent. 



The extracts from rice polishings seem to be particularly 

 active when tested on rats, and, by comparison, far less so when 

 tested on pigeons. 



209 (2169) 



Clinical results obtained with bacillus acidophilus. 

 By NICHOLAS KOPELOFF. 



[From the Department of Bacteriology, N. Y. State Psychiatric 

 Institute, Ward's Island, New York City.] 



1. A series of 30 constipated subjects were under observa- 

 tion before, during, and after treatment with B. acidophilus. A 

 comparison of these periods shows that the number of normal 

 defecations has been significantly increased during treatment. 

 The usual daily dose was 1,000 c.c. containing 200,000,000 

 viable B. acidophilus per c.c. 



2. The beneficial influence of B. acidophilus usually persists 

 for a considerable period of time after treatment has been stop- 

 ped. Patients have been observed for from one week to alxmt 



