468 



Scientific Proceedings (132) 



TABLE III. 



Groims I II III IV 



Serum a. b. x. b a. c. x. 



Corpuscles A. C. X. B A. B. X. 



According to our present knowledge the constitution of the 

 four blood groups, including the two new pairs of elements, 

 may be represented as in Table III. 



The possibility of this pair of isoagglutination elements being 

 identical with that described by Guthrie and Huck must be con- 

 sidered. The study will be pursued and a detailed report will 

 be made in the Journal of Immunology. 



231 (2191) 



A dangerous "universal donor" detected by the direct match- 

 ing of bloods. 



By PHILIP LEVINE and JENNIE MABEE (by invitation). 



[From the Department of Bacteriology and Immunology, Division 

 of Immunology in Cornell University Medical College, and 

 the New York Hospital.] 



In cases of transfusion where it is difficult to obtain a donor 

 of the same group as the patient, a person of Group I (Jansky) 

 has been considered suitable on account of the fact that the 

 corpuscles of this group are inagglutinable by the isohemagglu- 

 tinins. The fact that the plasma of a Group I individual con- 

 tain isoagglutinins capable of clumping the corpuscles of the 

 recipient has been ignored, because, under ordinary circum- 

 stances, the quantity of the plasma transfused is too small to 

 affect the larger proportion (five to ten times) of the recipient's 

 corpuscles. 



In carrying out the method of direct matching of bloods de- 

 scribed by Coca, 1 we found that the plasma of one of us (M., 

 Group I) produced complete agglutination of ten volumes of 

 the corpuscles of P. L. (Group II). Quantitative tests in the 



i Bef. Journal of Immunology, 1918, 93-100. 



