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Scientific Proceedings (132) 



stance is white, and of a starchy character. It melts at 94.5°- 

 96° C. It is readily soluble in alcohol, acetone, pyridin, slightly 

 soluble in ether, and is insoluble in ligroin, alkalies or water. 



(2.) Tetra-para-nitro-benzoylphloridzin : This was ob- 

 tained in a manner analogous to that of the preceding substance, 

 by the reaction of para-nitro-benzoyl chloride on phloridzin in 

 pyridin. This substance is amorphous in character, and of a 

 greenish yellow color. Melting point is 122° C. It is readily 

 soluble in pyridine, less so in boiling alcohol and acetone ; slight- 

 ly soluble in ether, and insoluble in ligroin alkalies and water. 



(3.) Pentapalmitylphloridizin : Was prepared from phlo- 

 ridzin and palmitylchloride in pyridin solution. It forms a 

 slightly yellowish amorphous product, melting sharply at 51.5° C; 

 easily soluble in chloroform, alcohol, ether, acetone, pyridin and 

 ligroin. 



(4.) Sodium phloridzin-tris-azobenzene : Was prepared in 

 an alkaline medium by the reaction of diazobenzene sulfate with 

 phloridzin. The substance forms a bright red amorphous mass, 

 which is readily soluble in ethyl alcohol, methyl alcohol, acetic 

 acid, acetone and ether ; it is insoluble in ligroin and water. Di- 

 ute alkalies dissolve it with the formation of a dark red color. 

 Concentrated sulfuric acid dissolves it, giving the solution a deep 

 red color. This substance turns dark at 190° C. and at 405° C. 

 it decomposes. 



Three other new compounds have been prepared; their chem- 

 ical constitution, however, has not as yet been definite estab- 

 lished: (1) phloridzin-sulfanildiazotate, (2) phloridzin- 

 diazoorthotoluene, (3) phloridzin-diazoparatoluene. 



A complete report of the methods used in the preparation of 

 the above substances, as well as their physical properties and 

 chemical constitution will be presented in another place. The 

 pharmacological action of these compounds will be reported 

 later. 



We wish to express our thanks to Dr. A. Elek of the Rocke- 

 feller Institute for the combusion analyses of these new com- 

 pounds. 



