68 



Scientific Proceedings (63). 



45 (977) 



The influence of the anterior lobe of the pituitary body upon the 

 growth of carcinomata. (Preliminary Communication.) 



By T. Brailsford Robertson and Theodore C. Burnett. 



[From the Rudolph Spreckels Physiological Laboratory of the Univer- 

 sity of California.] 



We have found that the administration of aqueous emulsions 

 of the anterior lobe of the ox-pituitary, in doses of 0.5 grammes of 

 fresh glandular tissue at intervals of two or three days, either 

 directly into the tumor or hypodermically elsewhere, leads to a 

 very marked increase in the rate of growth of the primary tumor 

 in rats inoculated with the Flexner-Jobling carcinoma. The 

 growth of small tumors is accelerated relatively more than that 

 of large tumors. 



This acceleration is only evidenced, however, at a certain stage 

 in the growth of the tumor, subsequent to the twentieth day 

 succeeding inoculations. The administrations do not enhance 

 the tendency of the tumors to metastasize. 



Liver-emulsion, similarly prepared and administered, does not 

 cause any acceleration of the growth of carcinomata in rats. 



46 (978) 

 Cholesterol atheroma in rabbits. 



By C. H. Bailey, M.D. (by invitation). 



[From the Pathological Laboratory of Stanford University Medical 



School.] 



The experiments of Ignatowski and Chalatow in which they 

 produced atheroma of the aorta by feeding rabbits on egg yolk 

 or pure cholesterol have been repeated. Each of a series of rabbits 

 was given the yolk of one egg daily mixed with its ordinary food. 

 Other rabbits received daily from 0.2 to 0.5 gm. of pure cholesterol 

 dissolved in cotton seed oil, mixed with their regular food. Three 

 rabbits have thus far come to autopsy: one which had been on an 



