Cerebellum in Cases of "Shock." 8i 



The one dog of series 5 was killed at the end of the experiment. 

 The blood-pressure was not recorded. 



Results of the Microscopical Examination of the Cerebella 

 in the Five Series. 



I would say that owing to a mistake on my part three of the 

 brains were perfused by a solution of formaldehyde of only a little 

 over 1 per cent, and afterward placed in this weak fixative, I 

 thinking that 10 per cent, had been ordered. These specimens 

 were two in series 1 (S. 155 & S. 158) and one in series 3 (P. 3). 

 These specimens must be discarded from any consideration as 

 post-mortem change is quite evident. In series 1, one specimen 

 (S. 212) has been over differentiated so that new material will 

 have to be prepared before judgment can be passed as to the con- 

 dition of the Purkinje cells. 



This leaves ten specimens in series I (S. 140, S. 145, S. 150, 

 P. I, S. 171, S. 176, S. 184, S. 187, S. 213, and S. 218) on which 

 I would report as follows: 



In specimen S. 218 the Purkinje cells show a much greater 

 percentage of type /3 cell than is normally found. Moreover the 

 pyknomorphous cell predominates. What is possibly furthest 

 from normal is a pronounced vacuolization which one finds in 

 these sections more than occasionally. 



It will be noted that the dog of this experiment was not killed 

 until 20 hours after the completion of the work. This is a factor 

 which can not be set aside. 



All of the other specimens of this series can be pronounced 

 normal. I would call attention to the gross appearance of the 

 staining in P. 1, which shows well the deeper staining of the 

 paraflocular granules than elsewhere in the cerebellum. This is a 

 normal finding. 



In series 2 the following report can be made: — 



P. 9 appears normal. This animal's blood-pressure was from 

 20 mm. to 40 mm. S. 219 appears normal. The blood-pressure 

 in this case was 50 mm. to 70 mm. P. 5 appears normal. The 

 blood-pressure was 25 mm. to 40 mm. Concerning P. 4, Dr. 

 Jackson records on the chart: "Poor transfusion." But this can 



