Circulation Changes Following Intestinal Trauma. 87 



53 (985) 



Changes in the peripheral circulation following intestinal trauma. 



By Walden E. Muns (by invitation). 



[From the Department of Physiology, University and Bellevue 

 Hospital Medical College.] 



This investigation had for its purpose the demonstration of the 

 actual changes in the condition of the peripheral circulation fol- 

 lowing severe manipulations of and trauma to the intestines. 



The term peripheral is employed to include the musculature of 

 the extremities and trunk. 



Many statements have been made by various investigators 

 as to the actual condition of the peripheral vessels after shock has 

 been brought about by intestinal trauma, but, with few exceptions, 

 such changes have not been clearly demonstrated. Some have 

 apparently concluded that the vessels in the periphery following 

 long-continued intestinal trauma are dilated, 1 while fully as 

 many 2 maintain that this is not true. 



Relation of Time, Volume and Blood Pressure. 



Length of Experi- 

 ment, Minutes. 



Fall in Volume at End of 

 Experiment in c.c. 



Beginning. 



Blood Pressure. 



End. 



52 



3 



87 



70 



45 



2 



110 



115 



165 



5 



133 



131 



120 



10 



106 



105 



SO 



0 



91 



65 



5i 



9 



115 



135 



92 



5 in 31 min., 10, at death 



107 



118 in 31 minutes 



Dogs were used, the anesthetic in each case being ether ad- 

 ministered by intratracheal insufflation preceded by physiological 

 doses of morphine and curare. The blood pressure was taken 

 from the carotid artery. A specially made plethysmograph was 

 placed around the leg to above the knee, and was connected with a 

 water manometer which was calibrated. Readings gave changes 

 in volume of the leg. 



1 Mummery, The Lancet, 1905, 696; Meltzer, Arch. int. Med., 1908, I, 571. 



2 Malcolm, The Lancet, 1905, 573; Seelig and Lyon, Jour. A.M. A., 1909, 52, 45. 



