214 



Scientific Proceedings (68). 



129 (1061) 



On sub-muscular skin transplantations. (Preliminary note.) 



By Harry Carson Coe. (By invitation.) 



[From the Department of Bacteriology and Immunity, Leland 

 Stanford Jr. University.] 



Skin transplantations on smaller laboratory animals are 

 usually unsuccessful due to difficulties of bandaging and im- 

 mobilization. As a preliminary to certain immunity studies an 

 operation has been devised to avoid these difficulties, the animals' 

 own tissues being used as a means of immobilization and surgical 

 dressing. 



On guinea-pigs, for example, an incision is made in the mid- 

 dorsal line and the skin and superficial muscles resected. The 

 skin graft is placed in the sub-muscular pocket thus formed and 

 fastened to the periostium of the ribs with silk sutures. The 

 resected tissues are drawn up over the graft and the dorsal incision 

 permanently closed. 



About a week later, the superficial tissues are resected over 

 the graft, and the edges of the resection wound sewed to the graft 

 with silk sutures. The exposed graft is protected for a week or 

 two with a light dressing of silver foil and cotton. 



The results of the operation are good, so far as the initial 

 union of tissues is concerned. 



130 (1062) 



On the reaction of the anaphylactic uterus in situ. (PreUminary 



note.) 



By William H. Moore and Yoshio Kusama. (By invitation.) 



[From the Department of Bacteriology and Immunity, Leland 

 Stanford Jr. University.] 



Strips of the anaphylactic guinea-pig uterus contract strongly 

 when tested with the foreign proteid toward which the guinea-pig is 

 sensitive. Our attempts thus far to record similar contractions by 

 applying the proteid to the uterus in situ have been unsuccessful. 



