78 



Scientific Proceedings (72). 



in cm., the abscissae the weight in kilograms and curved lines 

 drawn diagonally across the chart give the readings for the surface 

 area in square meters. The details of the work with the chart 

 and values of the constants will appear shortly in the Archives of 

 Internal Medicine. 



46 (11 10) 



Diabetic dietetics. Glucose formation from protein foods. 



By N. W. Janney and F. A. Csonka (by invitation.). 



[From the Chemical Laboratory of the Montefiore Home and Hospital, 



New York City.] 



The carbohydrate content of foods has been usually accepted 

 as a gauge of their adaptability to the dietary of diabetics. It 

 has, however, been demonstrated that proteins yield in the glyco- 

 suric organism large amounts of glucose (50 to 80 per cent, of their 

 weight, Janney). An exact knowledge of how much sugar arises 

 in diabetic metabolism from protein food is therefore of some im- 

 portance. 



By observing certain precautions it was found possible to 

 determine rather accurately the amounts of glucose yielded by 

 various meats fed to dogs made completely diabetic by phlorizin. 

 The sugar formed from beef, chicken, chicken eggs, rabbit and fish 

 could thus be ascertained to represent from 9 to 12 per cent, of 

 the uncooked moist food. The solid substances of these materials 

 produced from 36 to 48 per cent, glucose. Broiling and frying 

 lead to considerable loss of water with corresponding increase of 

 the percentage formation of glucose. Broiled beefsteak would 

 yield 17.5 per cent, glucose. 



Flour fed in preliminary experiments of the same nature gave 

 rise to 92.5 per cent, of sugar on an anhydrous basis of calculation. 

 From this data it was computed that in regard to sugar production 

 or liberation in the organism 100 gm. bread is equivalent to about 

 350 gm. broiled beefsteak. In formulating diets for diabetics, 

 glucose formation from the protein as well as the carbohydrate 

 content of the food should therefore be considered. The experi- 

 ments here alluded to will be later reported in detail. 



