Digestibility and Utilization of Egg-Proteins. 155 



type, but the blood sugar curve was higher and of longer duration. 



Cases of diabetes with signs of nephritis showed an initial high 

 blood sugar with comparatively low urine sugar. The blood sugar 

 curve increased at about the normal rate but return to normal did 

 not take place before 4^ to 6 hours. The urine sugar curve was 

 low, the highest concentration being 1.5 per cent., although the 

 blood at that time contained 0.31 per cent, sugar. 



Cases of chronic nephritis showed an initial high blood sugar, 

 0.16 per cent., with urine normal. Alimentary hyperglycemia 

 was delayed and prolonged, the highest point being reached in 

 2 hours and return to normal not taking place before 4 to 6 hours. 

 The highest point in the urine sugar curve was 0.5 per cent., the 

 blood at that time containing 0.37 per cent. 



A case of chronic parenchymatous nephritis showed a constant 

 glycosuria of 0.5 per cent. This was independent of the blood 

 sugar up to the latter's concentration of 0.21 per cent. In a 

 second test where the blood sugar reached 0.4 per cent, the urine 

 sugar increased to 1.0 per cent., later decreasing and continuing 

 at 0.5 per cent., the blood containing 0.2 per cent. 



Cases of myxedema and hypopituitarism were also studied. 

 In these cases the initial blood sugar and urine sugar values were 

 normal. Alimentary hyperglycemia was delayed and prolonged 

 as in nephritis and kidney permeability was greatly decreased. 



86 (1150) 



The digestibility and utilization of egg-proteins. 



By W. G. Bateman. (By invitation.) 



[From the Sheffield Laboratory of Physiological Chemistry, Yale 

 University, New Haven, Connecticut.] 



Raw egg-white is found to be a decidedly indigestible sub- 

 stance. It may cause diarrhea in dogs, rats, rabbits and men 

 when ingested in any large quantity. Its utilization by the body 

 is poor since it is used only to the extent of from 50 to 70 per cent. 

 Subjects can acquire a certain tolerance for the native protein 

 after ingesting it for several days so that it no longer causes 

 diarrhea and is somewhat better utilized. 



