194 



Scientific Proceedings (76). 



no (1174) 



On the transformation of the plasma clot. 



By George A. Baitsell. (By invitation.) 



[From the Osborn Zoological Laboratory, Yale University, New 

 Haven, Connecticut.} 



It has previously 1 been shown by the author that in tissue 

 cultures and in wound healing in the frog a fibrous tissue which is 

 apparently identical with normal connective tissue may be formed 

 by a direct transformation of a plasma clot. In an endeavor to 

 analyze this reaction, plasma clots made from centrifuged blood 

 plasma have been subjected to various conditions of tension and 

 pressure. The results obtained show that with the aid of these 

 mechanical factors it is possible to directly transform a typical 

 fibrin net into a fibrous tissue. Judged from its histological 

 structure when stained with Mallory's connective tissue stain, 

 this new fibrous tissue is apparently identical with normal con- 

 nective tissue of the frog. By varying the conditions it is possible 

 to obtain preparations which will show various stages in the trans- 

 formation ranging from a typical fibrin net to a fibrous tissue made 

 up of bundles of wavy fibers such as is characteristic of normal 

 connective tissue. 



in (1175) 



The effect of moderately high atmospheric temperatures upon 

 the formation of agglutinins. 



By C.-E. A. Winslow, James Alexander Miller, and W. C. 



Noble. 



[From the New York State Commission on Ventilation.] 



In an earlier communication 2 we have pointed out that previous 

 experiments on the effect of atmospheric temperature upon the 

 development of various immunity reactions suggest two general 

 conclusions: (1) That very high atmospheric temperatures, 

 over 35 0 C, tend to produce a condition of fever and to hasten 



1 (a) Jour. Exp. Med., Vol. 21, 1915, pp. 455-479; (£>) Jour. Exp. Med., Vol. 23, 

 1916, pp. 439-456. 



2 Proc. Soc. Exp. Biol, and Med., 1916, Vol. XIII, p. 93. 



