Effects of Castration on Cockerels. 3 



0.5 gram per kilo in three; less than one gram per kilo in two tests; 

 and 1.5 grams per kilo in one test. 



Morphin Hyperglycemia. 



No. 



AK 5 . 



AK 32 . 



Con- 

 trol 1. 



Con- 

 trol 3. 



AK5. 



AK 37 . 



Con- 

 trol 3. 



Con- 

 trol 4. 



BD 3 . 



AK40. 



Con- 

 trol 7. 



Con- 

 trol 8. 



Dose per kilo . . 

 Normal 



2 mg. 

 0.130 



0.206 

 0.246 

 0.275 



0.240 



2 mg. 

 0.192 



0.230 

 0.270 

 0.315 



0.322 



2 mg. 



O.II2 



O.097 

 O.131 

 O.128 

 O.I19 



2 mg. 

 0.108 



O.III 



0.133 

 0.151 

 0.127 



1 mg. 



O.III 



2 mg. 

 0.109 



2 mg. 

 O.IOI 



2 mg. 

 0.090 



I mg. 

 0.125 



1 mg. 

 0.109 



i mg. 

 0.104 



i mg. 

 0.114 



0.5 hr. after 

 morphin. . . . 

 1 hr. after 



0.171 

 0.209 



0.210 



0.238 

 0.297 



0.227 



O.128 

 0.124 

 O.I06 



0.144 

 0.138 

 0.123 



0.213 



0.197 

 0.124 



0.096 

 0.141 

 0.130 



0.107 

 0.136 

 o.i57 



0.087 

 0.115 

 0.109 



2 hrs. after. . . . 



3 hrs. after. . . . 





All dogs fed 5 hours 

 previously 



Not fed 

 to-day 



Starved for 

 8 days 



All dogs not fed 

 to-day 



AK5: pancreas coagulated in situ with alcohol, 119 days before morphin test. 

 AK32: pancreas coagulated in situ with alcohol, 51 days before morphin test. 

 AK37: pancreas resected; uncinate process transplanted beneath skin 41 days 

 before test. 



BD3: five sixths of pancreas resected 90 days before; remaining sixth in connection 

 with ducts. 



AK40: uncinate process and tail of pancreas merely ligated 60 days before test. 

 Control dogs, normal animals, some were fasted. 

 Operated dogs all fed on regular mixed diet. 



Blood samples from external jugular vein. Sugar determination by Myer's and 

 Bailey's modification of the Lewis-Benedict method. 



Whether the test will yield the same results in the human 

 subject which we have obtained in dogs, can only be determined 

 by trial, and such a trial we believe fully warranted by our findings. 

 The procedure can easily be carried out with less than one cubic 

 centimeter of blood if the Epstein method, for example, is used 

 for determining the blood-sugar. The dose of morphin probably 

 need not exceed 15-20 milligrams for an adult. The discomfort 

 from the morphin will surely be considerably less than that 

 following the ingestion of 1 to 200 grams of dextrose. 



107 (1285) 



Demonstration of the effects of castration on Seabright cockerels. 

 By T. H. Morgan. 



[From Columbia University, New York City.] 



Two years ago I demonstrated before this Society castrated 

 Fi and F 2 cockerels that had been hen-feathered, but which in 



