Studies of Dental Caries. 



5 



and glycosuria were studied after painting the pancreas. In the 

 main we could not confirm these claims, but we wish however to 

 mention here only one striking result. In eight experiments in 

 which the pancreas was so isolated from the peritoneum that 

 none of the adrenalin could enter the peritoneal cavity, the 

 hyperglycemia as well as the glycosuria produced by the painting 

 was insignificant, surely not more than would have occurred if 

 the adrenalin had been given subcutaneously or painted on some 

 part of the peritoneum. 



109 (1287) 



Studies of dental caries, with special reference to internal secre- 

 tions in their relation to the development and condition 

 of dental enamel. 



By William J. Gies and Collaborators. 



[From the Biochemical Laboratory of the Schools of Medicine and 

 Dentistry of Columbia University, College of Physicians 

 and Surgeons.] 



A. Do substances in the blood pass from dental pulp into dental 



enamel of living animals? Hattie L. Heft. 



B. Is dental enamel permeable to substances in saliva? Elizabeth 



C. Franke. 



C. Effects of parathyroidectomy and castration on dentition in 



albino rats. Edgar G. Miller, Jr. 



D. Dental effects of feeding glandular tissues to albino rats- 



Edgar G. Miller, Jr. 



E. A new glycoprotein : dentomucoid. Leila Noland. 



Decay of teeth, except that arising from trauma, may be due, 

 primarily, to local deficiency in the structure and quality of 

 enamel, or it may result from local specific disintegrative attack 

 on enamel, regardless of normality of the enamel, or it may be 

 caused by both these types of influences. In this series of studies 

 we are endeavoring to ascertain whether "influences from the 

 inside," such as those of a nutritional type and involving internal 

 secretions, may be responsible factors in the incidence of dental 

 caries. 



