4 6 



Scientific Proceedings (87). 



or more, and very often not at all unless the catheter be removed. 

 If, on the other hand, the urethra of the same dog, on another 

 day, be irrigated with the same solution or even weaker solutions 

 of apomorphin, care being taken not to inject the drug into the 

 bladder but to confine the irrigation only to the urethra and 

 allow the fluid to run back, vomiting is produced in every case in 

 from three to five minutes. Inasmuch as vomiting is produced in 

 dogs almost as efficiently by means of morphin as with apomorphin, 

 the same results can be obtained by using that alkaloid. Even 

 strong solutions of morphin confined to the bladder produce either 

 no vomiting at all or only after the lapse of a considerable period 

 of time (half an hour to one hour). On the other hand, the 

 introduction of a little morphin solution into the urethra is 

 followed in the dog by vomiting in a few minutes. The remark- 

 able difference in the absorptive power between the urethra and 

 the bladder noted after morphin and apomorphin, holds good for a 

 large number of other drugs and poisons. The author has studied 

 in this connection the effect of various alkaloids, a number of 

 antiseptics, some local anesthetics and a number of salts. The 

 complete account of the investigation will be published in due time 

 in the Journal of Urology. It may be stated in this place that 

 an inquiry into the absorptive power of the ureters is also under 

 investigation by the author. 



135 (1313) 



On the influence of some opiates and antipyretics on the field of 



vision. 



By David I. Macht, S. Isaacs, and J. P. Greenberg. 



[From the Pharmacological and Psychological Laboratories, Johns 

 Hopkins University.] 



While the effect of drugs on the acuity and field of vision has 

 as yet not been the subject of extensive study, the work extant, 

 such as, for instance, that of Dreser 1 on the influence of strychnin 

 on the visual function, indicates that important changes in visional 

 perception may be produced by the ingestion of pharmacological 

 agents. In connection with an extensive study of the effect of 

 various antipyretics on different psychological functions, the 



1 Dreser, 1894, XXXIII, 251. 



