133 



Scientific Proceedings (92). 



morning a Rehfuss tube is inserted into the stomach of the patient. 

 The patient is then given an Ewald test meal, and the gastric and 

 duodenal contents removed simultaneously at varying intervals 

 of time. The extractions are usually made every fifteen minutes 

 for a period of two and a half or three hours. The gastric contents 

 are analyzed for the acid secretions and the enzymes. The duode- 

 nal contents are analyzed for the various enzymes. The results 

 are charted in the form of a curve. 



A gastro-duodenal tube has been devised which obviates the 

 necessity of passing two tubes. This tube is composed of two 

 compartments — one ending ten inches above the duodenal opening. 

 The tube bifurcates at its free end, and the openings are distinctly 

 labelled G and D to indicate the opening leading to the stomach 

 and to the duodenum. 



The clinical and physiological results of the study of the gastric 

 and duodenal secretions by this method will soon be reported. 



191 (1369) 



Studies on the metabolism of cells in vitro. The toxicity of 

 dipeptids for embryonic chicken cells. 



By Montrose T. Burrows and Clarence A. Neymann. 



[From the Pathological Laboratory, Washington University Medical 

 School, St. Louis, Mo., and the Laboratory of Internal Medicine, 

 Henry Phipps Psychiatric-Clinic, The Johns Hopkins University, 

 Baltimore.] 



In a previous paper 1 we have shown that peptone prepared from 

 the yolk of egg is non-toxic for growing chicken cells even when 

 added in considerable concentration to the medium. Egg yolk 

 digested to the point of crystallizing out an a-amino acid is toxic. 

 We tested a large number of a-amino acids and have found that all 

 are toxic for the cells. In low dilution they stimulate the con- 

 traction of heart muscle fragments but did not affect the growth. 

 In higher dilution they inhibit the growth of cells completely 

 and killed. 



Having established this fact it became of interest to study the 



1 Jour. Exp. Med., 1917, Vol. XXV., pp. 93-108.- 



