64 ( 1 28) Society for Experimental Biology and Medicine. 



then repeatedly with 85^0 alcohol, at the boiling points, and the 

 extracts filtered from the coagulum on a hot-water funnel. The 

 filtrates were cooled to from o° C. to — 5 0 C, the precipitate was fil- 

 tered out and purified by boiling with absolute alcohol, diluting the 

 filtrate with water to make 85^ alcohol, chilling, filtering, treating 

 the precipitate repeatedly with cold ether to remove cholesterin, 

 dissolving in hot chloroform, reprecipitating by chilling, filtering 

 and expressing all possible traces of chloroform. The resulting 

 product is a white, somewhat crystalline substance, freely soluble 

 in warm 85^ alcohol or chloroform, but reprecipitating upon cool- 

 ing. It contains fatty acids, phosphorus, methyl, sulfur, and, upon 

 cleavage with dilute sulfuric or hydrochloric acid, yields a reducing 

 substance from which an osazone may be prepared. 



For purposes of comparison, a similar substance was prepared 

 from beef brains, with the same method. Analyses of these prod- 

 ucts, two from different lots of beef kidneys and one from beef 

 brains, were kindly made for the author by Dr. Phoebus A. Le- 

 vene, with the following percentage results : 





From Beef Kidney. 



From Beef Brain. 



Cramer's Figures for Prota- 

 gon from Beef Brain. 





(1) 



(2) 







c 



65.61 



65-55 



65.76 



66.25-66.42 



H 



11.00 



I I.09 



IO.66 



IO. 82-11. 07 



N 



3-I7-3-I5 



3.24-3.26 



2.51 



2.29 



P 



2.06 



2.19 



O.97 



I.04 



S 



O.82 





i-33 



O.7I 



The substance from the kidney contains distinctly more nitro- 

 gen and phosphorus than that from the brain, and that obtained 

 by the author from the brain contained considerably more sulfur 

 than that prepared from the same source by Cramer. The cleav- 

 age products, however, show that all of these substances belong 

 in the same group. The nature of the glucosid which may be 

 obtained from these substances can only be determined by using 

 larger quantities than have as yet been obtained, and the author 

 hopes to report results in this direction in the near future. 



30 (76). " Comparative physiological action of salts of neodym- 

 ium, praseodymium and lanthanum " : B.J. DRYFUSS and 

 C. G. L. WOLF. 



The experiments were undertaken to investigate the compara- 



