48 Society for Experimental Biology and Medicine. 



after instillation some dilation may be perceptible as long as 36 

 hours. The maximum dilation may even continue as long as 12 

 hours. 



When the cord is severed just below the medulla oblongata, 

 the pupils usually become small and ellipsoid in shape. A sub- 

 cutaneous injection causes them to become wide and round. In- 

 stillation has the same effect. Finally, the effect of instillation 

 can be well shown also on the excised eyes, even when the ad- 

 renalin is applied some hours after excision, provided the eyes are 

 kept moist. The experiments were demonstrated. 



