Waves of Blood Pressure. 57 



29 (1776) 



On the relation of blood-volume to the nutrition of the tissues. 



IV. The effects of hemorrhage and subsequent injection of gum- 

 saline on total oxygen consumption. 



By ROBERT GESELL, CHARLES S. CAPP and FREDERICK S. "FOOTE. 



[From the Department of Physiology, University of 

 California, Berkeley, California.] 



The effects of progressive hemorrhage were studied on the 

 dog under morphine-urethane anesthesia. We found that the 

 greater the hemorrhage the greater the reduction in the amount 

 of oxygen consumed and that a hemorrhage amounting to 1/2 per 

 cent, of the body weight may elicit a decided reduction. Sub- 

 sequent injection of gum-saline, bringing the blood volume back 

 to normal, increased the amount of oxygen consumed. The 

 amount of oxygen consumed immediately after an injection was 

 greater than the consumption a few minutes later. We believe 

 this, along with the decreased amount of oxygen consumed, points 

 to an oxygen hunger during a period of decreased blood-volume. 

 The results here reported are in agreement with those recently 

 published by Doi. 1 



30 (1777) 



A comparison of the waves of blood pressure produced by slow 

 and by rapid breathing. 



By ROBERT TROTTER, PHILIP EDSON and ROBERT GESELL. 



[From the Department of Physiology, University of 

 California, Berkeley, California.] 



The effects of rapid breathing were compared with those of 

 more normal breathing upon the systolic blood pressure in man. 

 Supplementary data were also obtained on the dog and cat. 



For the well-known changes of blood pressure that occur during 

 a single respiration, and which are more or less synchronous with 

 the changing respiratory phases, we have proposed the name of 

 simple cardio-respiratory waves to distinguish them from those 

 waves produced by rapid breathing. 



1 Doi, Y., Journal of Physiology, 1921, lv, 249. 



