Bacterial Action of Aromatic Compounds. 67 



oc b h 9 

 /\ CH2OH 



12. Saligenin iso amylether | | 



Sat. sol. less than i : ioooo. 

 Pneumo — after 5 min. 



Gono — after 10 min. 



Staphylococcus and Bacillus colt 



both + after 30 min. 



OOCCH3 

 \ CH 2 OH 



13. Acetyl saligenin 



1: 200 Pneumo — after 5 min. 

 Gono — after 10 min. 



From the above- recorded experiments it is evident that in the 

 simpler aromatic substances, predominantly water-soluble like 

 sodium phenolsulphonate and salicylate or predominantly lipoid- 

 soluble like para amino phenol and para nitrophenol, whether 

 nitrogen-free or containing nitrogen, the introduction of an ethyl 

 group upon the ring does not confer pneumococcicidal or gonococci- 

 cidal powers. Whenever any difference is noted the hydroxy 

 compound is a somewhat stronger antiseptic than the ethoxy. 

 There is therefore no analogy in this regard between the simpler 

 aromatic compounds and the quinine derivatives. 



