Inheritance of Susceptibility. 165 

 table 1. 



Cross No. 



Races. 



Autotrans- 

 plants. 



Homiotrans- 

 plants. 



+ 





+ 





I 



Japanese waltzing X Japanese waltzing 



22 



1* a 



22 



i*a 



2 



Japanese waltzing 

 X albino 



14 



16 



i*b 



l*C 



0 

 0 



i 5 *b 

 I7*c 



3 



Japanese waltzing 

 X Fi hydrids 



23 



33 



0 

 0 



0 



33 



23 



0 



+ means persistence of the implant in a healthy condition. 

 — means disintegration of the implant. 



*a — Mouse sick and probably unable to provide adequate nourishment for 

 either implant. 



*b — One mouse negative to both auto and homio, probably due to poor operative 

 technique or to mouse being in poor physical condition. 



*c — One mouse negative to both auto and homio, probably due to poor operative 

 technique or to mouse being in poor physical condition. 



These results are tabulated in the top two lines of Table I. 

 It should be noted that in one animal neither the autotransplant 

 nor the homiotransplant persisted. Records show that this ani- 

 mal was in markedly poor physical condition and this without 

 doubt accounts for the elimination of both implants. 



When interchange of splenic implants was made between 

 Japanese waltzing mice and unrelated albino non-waltzers, the 

 results shown in lines 3 and 4 of Table I were obtained. 



One Japanese waltzing mouse and one albino failed to support 

 either the auto or the homio implant. This was probably due to 

 poor technique involving infection after the operation. If these 

 animals are subtracted from the totals we find that the auto- 

 transplants in either the Japanese waltzers or the albinos are 

 successful, while the homiotransplants from albino to waltzer or 

 vice versa are uniformly unsuccessful. 



This, it will be remembered, is the result ordinarily obtained 

 in homiotrans plantation and adds another piece of evidence to our 

 belief that similarity in genetic constitution is essential for success- 

 ful implantation of splenic tissue. 



The interesting and crucial test of the correctness of the 

 hypothesis on which the experiments were planned is found in th e 



