Absorption of Glucose Given by Rectum. 



293 



men collected just before the enema was given, and for the speci- 

 men which corresponded to the period during which the enema was 

 retained. Both tables show that there was a decrease in the 

 concentration of acetone plus acetoacetic acid caused by the 

 glucose, while the 0-hydroxybutyric acid did not show the increase 

 which is usually caused by such diets. 1 The decrease was not as 

 great as that caused by similar amounts of glucose when taken by 

 mouth. Shaffer 2 has recently advocated the theory that the 

 failure of acetoacetic acid to burn completely in the absence of 

 glucose is responsible for the appearance of increased amounts of 

 the acetone bodies in the urine. The observation that the aceto- 



TABLE I. 





Urine. 





Date, 



Vol. 



Acetone. 



/3-hydroxy. 



Alv,C0 2 



1921. 



c.c. 











mm. 







rag. 



gms. 



mg. 











100 c.c. 



100 c.c. 



gms. 





i5-i6» 



910 



1.1 



0.010 



1-7 



0.015 



40 



16-17 



780 



3-6 



0.029 



2.7 



0.021 



36 



17-18 



770 



7-8 



0.060 



3-4 



0.026 







852 



25.2 



0.215 



11.9 



O.IOI 



32 





628 



18.7 



0.118 



15.2 



0.096 





300 c.c. 5 per cent, glucose at 9:30 A.M. on December 19. 

 Results of the determinations of the acetone bodies are expressed in terms of 

 acetone. Under acetone the results of the determination of acetone from acetone 

 plus acetoacetic acid are given. 



TABLE II. 







Urine. 



Date, 

 1921. 



Time, 

 A.M. 



Vol. 

 c.c. 



Acetone. 



/9-hydroxybutyric 

 Acid. 



mg. 



gms. 



mg. 



gms. 



100 c.c. 



100 c.c. 



12/18. . . . 



8:30 to II 



102 



19.2 



0.020 



13-3 



0.014 



12/19 



8:30 to 9:30 



40 



130 



0.005 



5-5 



0.002 



12/19 



9:30 to 12 



108 



7-8 



0.008 



4.6 



0.005 



300 c.c. of 5 per cent, glucose given by rectum at 9:30 A.M. on December 19. 



1 Hubbard and Wright, loc. cit. 



2 Shaffer, loc. cit., p. 433. 



3 Day before the diet was taken. 



