382 



Scientific Proceedings (124). 



TABLE II. 



Seasonal Tide of Blood Phosphate (Inorganic). 





1921 

 June \ 



July 



Dec. 



Jan. 



Feb. 



Men. 



Apr. 



May 

 \ Mo. 



Drv M 



Raw M 



4-45 

 4.21 



4-33 



3-9i 

 3-87 

 3-98 



3-86 

 3-77 

 3-83 



3-64 

 3-68 

 3.81 



348 

 3-30 

 352 



3-45 

 3-46 



3.67 



3-95 



1 



186 (1933) 



Localized lesions in the corpora striata produced by buried radium 



emanation. 



By D. J. EDWARDS and H. J. BAGG 



[From the Department of Physiology and the Memorial Hospital, 

 Cornell University Medical College, New York City.] 



When a small glass capillary tube, containing about one milli- 

 curie of radium emanation, is imbedded in living tissues definite 

 localized destructive reactions occur, mainly due to the relatively 

 intense beta-ray radiation given off in the immediate vicinity' of 

 the tube. 



Bagg has shown that when normal brain tissue is thus treated, 

 and examined after a period of about two weeks, the tissue about 

 the tube is completely necrotic, and is surrounded by a broad zone 

 of polynuclear leukocytes beyond which there is some hyperemia- 

 The entire lesion is limited to an area 1 cm. in diameter. The 

 lesion is well localized, the brain cells beyond the one-centimeter 

 zone retain their normal morphological character. That the 

 lesion is practically entirely due to the irradiation of the radium 

 emanation, and not to the presence of the glass tube, or the trau- 

 matism incident to its insertion, has been satisfactorily proven by 

 control experiments. 



The lesion just described is not produced at the time the small 

 tube is placed in the tissues. From previous data obtained by 

 examining various radiated areas at different periods after the 

 time of insertion, it was found that the lesion slowly increased in 

 size. At the end of 24 hours the zone of necrosis about the tube 



