Morphology of Cystic Growths. 



401 



may have started. This is shown in the adjoining photograph, 

 taken 24 hours after inoculation with a virulent staphylococcus 

 culture, recently prepared from a .human throat: The epine- 

 phrin ear (the right) shows the 

 perforation of the ear by the in- 

 fection; whilst in the left ear, no 

 inflammation is visible on the 

 inner side, although the ear had 

 been equally wounded and inocu- 

 lated, but not treated with epine- 

 phrin. These differences persist 

 in the further course ; the ear that 

 had received epinephrin healing 

 more slowly than the other ear. 



Marked differences, although 

 not always quite as striking as 

 these, were obtained in five inoc- 

 ulated rabbits, and in four rab- 

 bits without artificial inoculation. 

 In only one rabbit did there fail 

 to be a striking difference between 

 the two ears. 



Injection of slightly acidulated 

 water, on the other hand, did not 

 influence the course, showing that the difference is due to 

 the epinephrin, and not to the volume or reaction of the fluid. 



The experiment illustrates the current conceptions as to the 

 origin of "colds," i.e. by increased susceptibility to infection, 

 through the reflex vasoconstriction of " chills." It also warns 

 against the indiscriminate local use of epinephrin in wounds, and 

 especially in catarrhs. 



199 (1946) 



Morphology of cystic growths in the ovary and uterus of the 



guinea pig. 



By G. N. PAPANICOLAOU and C. R. STOCKARD. 



[From the Department of Anatomy, Cornell University Medical Col- 

 lege, New York City.} 



The ovary in the guinea pig, as in most other mammals, fre- 



