4i6 



Scientific Proceedings (124). 



the administration of phenolsulphonephthalein the glomerular 

 capsule can be seen to be distended with pink fluid indicating that 

 it is excreted through the glomerulus in an alkaline urine. Rown- 

 tree and Geraghty 1 • 2 have previously shown that phenolsulphone- 

 phthlaein is excreted through the tubules of the kidney but made 

 no observations upon the excretion through the glomeruli. Under 

 direct observation phenolsulphonephthalein can also be seen in 

 the renal tubules, usually as a red dye indicating a deep alkalinity. 

 The tissues immediately surrounding the renal capillaries are in 

 some animals stained a diffuse red by the phenolsulphonephthalein 

 and in some a light yellow, indicating that the tissues are some- 

 times alkaline and sometimes acid to phenolsulphonephthalein 

 (sometimes more and sometimes less alkaline than Ph — 7.2) in 

 spite of the fact that there was in all cases free and fairly rapid 

 circulation visible through the capillaries. This indicates that the 

 reaction of tissue cells may be on the acid side of neutral in 

 spite of the fact that there is no actual asphyxia. 



206 (1953) 



A method for the volumetric study of the human hypophysis 

 cerebri with illustrative results. 



By A. T. RASMUSSEN and RUTH HERRICK. 



[From the Department of Anatomy, University of Minnesota Med- 

 ical School, Minneapolis, Minn.] 



The importance of the ductless glands in modern medicine 

 h as created a demand for more accurate data on these structures. 

 Hammar of Upsala has particularly stressed this point. The 

 need for quantitative facts is more urgent in the case of the hypo- 

 physis, or pituitary body, because this organ is composed of sev- 

 eral parts which are more or less distinct structurally, function- 

 ally and embryologically ; and because of the present tendency 

 to classify pituitary disorders from the standpoint of hyper- or 

 hyposecretion of each lobe, the time of onset with reference to 



1 Rowntree, L. G. and Geraghty, J. T., J. Pharm. and Exper. Therap., 1910. i. 



579- 



1 Rowntree, L. G. and Geraghty. J. T., Arch. Int. Med., 191 2, ix, 284. 



