430 



Scientific Proceedings (124) 



trie contents, or with the form of the acid curve. Determination 

 of the alkaline tide furnished a method for checking the findings 

 in the gastric juice, and has been found useful in establishing a 

 possible anacidity in cases where satisfactory gastric analyses 

 could not be obtained. 



212 (1959) 



The blood chemistry of thyroidectomized sheep. 



By AARON BODANSKY (by invitation). 



[From the Biochemical Laboratory, Department of Physiology and 

 Biochemistry, Cornell University Medical College, Ithaca, N. Y.] 



A study of the blood chemistry of Dr. Sutherland Simpson's 

 experimental flock has been undertaken as a part of a larger study 

 of the metabolism of thyroidectomized sheep. 



The flock consists of thyroidectomized individuals and normal 

 controls. The thyroidectomized sheep were operated on at dif- 

 ferent ages, and to some of them were later administered thyroxin, 

 thyroid gland or sodium iodide in the course of other experi- 

 mental work. These administrations were discontinued about 

 10 months before the beginning of this series of analyses. 



Some of the animals were withdrawn from the author's use 

 for shorter or longer periods, and others were used simultaneously 

 for other experimental work involving increased exercise. In the 

 preliminary tests no attempt was made to control the diet of the 

 animals in any manner. Later the uniform practice was adopted 

 of taking the blood after a night of enforced rest in the sheep pens 

 before the sheep were given their morning meal. Greater uni- 

 formity of results was then obtained and it became possible to 

 observe certain broad distinctions between the normal and oper- 

 ated groups. 



The blood was drawn from the jugular vein directly into tubes 

 containing finely powdered potassium oxalate, which were kept 

 in ice water until used for analyses. Folin and Wu's procedure 

 was employed. 



At this time enough determinations are available only for sugar 

 and N. P. N. Sugar was found to range between 0.06 and 0.07 



