The Uric Acid Excretion of Normal Men. 19 



then was required to ingest the diet selected during the course of 

 six periods of four days each. Ten university students served as 

 subjects. Quarters were provided where the men could easily be 

 observed as to certain regulations of sleep and diet. The body 

 weights of the subjects ranged from 53.1 kg. to 76.7 kg. and 

 their ages varied from 19 to 29 years. There were no athletes 

 among the subjects so that no individual took excessive or violent 

 exercise, but all lived the life of the average, normal university 

 student. The Folin-Shaffer method for the determination of uric 

 acid was employed. 



Conclusions. 



1. The average daily excretion of uric acid for ten men rang- 

 ing in age from 19 to 29 years, and fed a normal mixed diet, was 

 0.597 gram, a value somewhat lower than the generally accepted 

 average of 0.7 gram for such a period. 



2. The average daily protein ingestion for these same subjects, 

 when permitted to select their diet, was 91.2 grams or 1.33 gram 

 per kilogram of body weight. 



1 1 (349) 



Hemolysins in the sera of carcinoma and syphilis. 



By S. PESKIND. (By invitation.) 



[From Dr. Peskhid's Private Laboratory, Cleveland, Ohio.'\ 



A few years ago the writer commenced a research, the object 

 of which was to determine in what diseases hemolysins commonly 

 occurred and whether or not they were specific for these diseases. 

 The ultimate purpose was to obtain data that one could use in 

 diagnosis. 



A preliminary report was published.^ The work had to be 

 abandoned shortly thereafter. Since then, other investigators — 

 notably Kelling — have taken up the study of hemolysins in con- 

 nection with their use in diagnosis. 



It occurred to the writer that it would be very desirable to 

 determine the question as to the specific nature of the hemolysins 

 found in various diseases. With this object in view, a study of 



Peskind : American Medicine, 1903, v, p. 918. 



