Effects of Carbon Mon-oxide Poisoning. 71 



Typical experiment of first series. — February 19, 1908. Dog's weight 9.7 Kg. 

 Ether anasthesia. 



Time. 



Respiration. 



Pulse, 



Blood pressure in 

 mm. of Hg. 



Volume of air 

 (in c.c. ) re- 

 spired per 

 minute. 



Per cent, of Hb 

 saturated with CO. 



2. IS 



P. M. 



22 





140 



90 



1,750 





2.18 



< < 



I 



per cent. CO respired 



148 









2-35 





24 





90 



I 02"; 





2.50 



( < 



36 





164 



92 



2,000 



20 



3-05 



ii 



40 





180 



96 



2,125 





3.22 





45 





204 



104 



2,250 



47 



3-35 



ti 



41 





194 



94 



2,250 





3-45 





40 





166 



88 



2, 100 



54 



3-So 





36 





120 



72 



1.925 





3-55 



t( 



32 





82 



62 



1,650 



66 



3-58 



t ( 



8 



irregular 



56 



40 



1,175 





4-05 





10 



i c 



68 





750 



73 



4.08 



ft 



De 



ath 











Typical experiment of second series. — March 2, 1908. Dog's weight 6.6 Kg. 



Dog placed in air-tight cage through which the gas mixture was driven by means 

 of bellows, operated by a water pressure engine. The ventilation of the cage was 

 5,000 c.c. of air per minute. 



Time. 



Respiration. 



Pulse. 



General condition. 



M. 



M. 



10.30 A, 



10.35 

 1 1. 00 

 11.45 

 12.00 

 12.30 P. 

 12.45 



1. 00 



1.20 



1-35 



1- S5 



2.05 

 2.30 



2- 45 



3- 45 



4.00 



4- 25 



5-10 " 

 Next morning 



16 



0.4 per cent. CO respired 

 16 

 16 

 18 



17 

 21 

 18 

 16 



16 

 17 



16 



104 



104 

 116 

 124 

 140 

 170 

 182 

 208 



192 

 196 



180 

 166 



Dog in good condition. 



Dog comfortable and quite active. 



Lies quietly ; slightly drowsy. 

 Drowsiness marked. 

 Slight convulsion and vomiting. 

 Responds to sensory stimulus after 



long latent period. 

 Convulsions of clonic type. 

 Slightly comatose ; when called he 



only opens his eyes. 

 Coma quite deep. 



All muscles and sphincters relaxed. 



Taken out of cage. Blood sample 

 shows 52 per cent, of the Hb 

 saturated with CO. Dog placed 

 in warm place near radiator. 



Respiration slow and deep, 10-12 

 per minute. 



Dog began to move about. 



Able to stand up and walk but falls 

 frequently, due to lack of coordi- 

 nation. 



Walked about fairly well, but very 



slowly. 

 Dog perfectly well. 



