Acute Insufficiency of Right Heart. 



Ill 



Blood-pressure, mm. Hg. 



Maxinium. Minimum. Average. 



Before operation, 45 days no 80 90 



After " first period, 43 days 120 100 in 



'' " second period, 26 days 140 no 121 



" " third period, 31 days 150 no 125 



" " whole period 120 



He has gained from 12,770 grm. to 16,250 grm. and his urine has 

 been free from albumin for three weeks, but is increased in quan- 

 tity. A still more marked hypertension has been obtained in Dog 

 20, as the following table shows : 



Blood-pressure, mm. Hg, 

 Maximum. Minimum, Average. 



Before operation, 23 days 135 95 117 



After " 35 " 17s 130 150 



This dog is excitable and single readings are liable to vary 

 somewhat on this account, but the comparison of the averages, 

 based on eleven observations before and twenty-one after operation, 

 or of either the highest or lowest readings, all show a true hyper- 

 tension as a result of the reduction of functioning kidney substancs 

 by this method. This dog has a persistent albuminuria, with casts 

 and red blood cells, and a daily urine quantity of about 500 c.c. 

 The three remaining dogs have not been under observation long 

 enough, or have not had sufficient reduction of circulation, to give 

 definite results as yet. 



58 (396) 



The effect of experimental acute insufficiency of the right 

 heart upon the volume of the organs. 



By H. 0. THACHER, M.D. 



\_From the Laboratory of the Medical Clinic in Tubingen 7\ 



If a small balloon be introduced into the right auricle or ven- 

 tricle, its inflation interferes with the action of the right heart and 

 renders the heart insufficient to perform its normal work. The 

 effect of this upon the systemic circulation should be nearly simi- 

 lar to that caused by acute cardiac insufficiency in general. The 

 changes in the volumes of the brain, liver, spleen, kidney, and 

 extremity resulting from such cardiac obstructions were registered 

 by oncometry in rabbits, cats and dogs. 



The carotid blood-pressure, which was always registered as an 



