Immunization against Transplantable Cancer. 19 



treated groups. The mice were all young and thrifty; average 

 weight, 18 grams. The three series were inoculated with carci- 

 noma ten days later. The record of the tumors resulting from these 

 inoculations shows a definite immunity in the series treated with 

 homologous blood, but practically no difference between the 

 normal controls and those receiving injections of their own blood. 



These findings, then, indicate that immunity against trans- 

 plantable cancer in mice is, at least, not regularly induced by 

 injections of an animal's own tissues. A larger series would prob- 

 ably be necessary to determine the existence of individual varia- 

 tions in the reaction of animals to such injections. 1 



3 (622) 



Another case of sex-limited heredity in poultry. 

 By 0. B. DAVENPORT. 



[From the Carnegie Institution of Washington.] 



To the four or five described cases of sex-limited heredity 

 in poultry another is added. 



The Jungle-fowl and its derivative, the Brown Leghorn, have 

 the hackle and saddle feathered "laced" with red. The upper 

 wing coverts of the cock are also red, forming the "wing bar." 

 In the Dark Brahma, on the other hand, the red is not formed on 

 the hackle and saddle and is nearly absent on the wing bar of the 

 male, so that the red is replaced by white. 



If, now, a male Dark Brahma be crossed with a female Brown 

 Leghorn, or if the cross be made in the opposite direction, all sons 

 are white-laced; but the wing bar is red. Thus, in these sons 

 the white lacing is dominant but the white wing bar appears to 

 be recessive. The most important point, however, is that the 

 sons derived from the reciprocal crosses are practically indis- 

 tinguishable. 



With the daughters this is by no means the case. When the 

 father is white-laced, the daughter is also; but if the father is red- 



1 A second set of experiments has been done which shows a slightly larger per- 

 centage of resistant animals among those immunized with autogenous tissue than 

 among the normal controls. The difference, however, is not sufficiently striking to 

 influence the conclusion drawn from the first experiments. 



