26 



Scientific Proceedings (46). 



the adrenals to this tolerance. We have further determined that 

 section of the cord between the fifth and sixth cervical vertebrae 

 interferes with this tolerance of gas (air). After the removal of 

 the adrenals from two dogs carbon dioxide was tolerated up to 942 

 c.c. in one case and 952 c.c. in the other, in 1 hour and 23 minutes. 



Two dogs were injected with nitrogen. 1 One received 32 c.c. 

 in six minutes with marked depressions; the animal lived. Pant- 

 ing occurred. The other received 272 c.c. within 22 minutes 

 and died; panting was not noticed. The lungs were collapsed at 

 autopsy. 



The tolerance of oxygen was tested on two dogs. One received 

 150 c.c. slowly and survived. The other received 312 c.c. in 23^ 

 minutes and died. During the oxygen experiments, panting 

 occurred. The lungs were practically normal. 



The tolerance of hydrogen was tested in two dogs. In one 184 

 c.c. in 8 c.c. volumes were injected in 13H minutes. Each injec- 

 tion caused a moderate depression. 60 c.c. were given in 20 c.c. 

 volumes in 3J/2 minutes, and 20 c.c. in 5 c.c. volumes. The large 

 volumes caused great depression and almost death. In the other 

 dog 90 c.c. were injected in 7 minutes in 8 c.c. volumes without 

 harmful results. 



Sulphuretted hydrogen was used to study elimination on two 

 dogs. Three c.c. saturated H2S water were injected into the 

 femoral vein. The breath almost immediately blackened lead 

 acetate. Twenty-five minutes after tying and clamping off the 

 adrenals 3 c.c. more of saturated H 2 S water was injected and a 

 similar result was obtained. 100 c.c. of H 2 S water introduced 

 into the rectum did not give the reaction at the mouth in 25 

 minutes. In the other dog 30 c.c. of H 2 S water were injected into 

 the duodenum. In 8 minutes it was detected at the mouth. 



1 In every case morphin sulphate was given before etherization of the dog. 

 Each dog was killed and autopsied after the experiment. 



