Hormones of the Secretion of Milk. 



19 



pass down the cord, emerge in the splanchnics, and go to the liver 

 to increase the transformation of glycogen into glucose. It is 

 held by some that as the splanchnics contain the secretory fibers 

 of the adrenals, that these impulses from the glyco-secretory center 

 increase the amount of epinephrin, which mobilizes the glycogen 

 of the liver and thus produces a diabetes. It is well known that 

 epinephrin is a stimulant of the sympathetic nerves, hence it is a 

 stimulant of the splanchnics. We have found the injection of 

 glucose per jugular in the cat increases the amount of epinephrin 

 in the blood, as shown by the intestinal strip of the rabbit. Hence 

 we have here a circle: epinephrin stimulates the secretory nerves 

 of the adrenals to produce epinephrin, which via the glycogen of 

 the liver produces more glucose, which in its turn generates more 

 epinephrin. We have also found the other sugars to increase the 

 amount of epinephrin in the blood. Pilocarpin, skatol and indol 

 also augment the amount of epinephrin in the blood. 



13 (709) 



Preliminary note on the inhibitory and synergistic hormones of 

 the secretion of milk. 



By Isaac Ott and John C. Scott. 



[From the Laboratory of Physiology, Medico Chirurgical College, 



Philadelphia] 



We have studied on the goat the hormones which inhibit the 

 milk secretion. We have found that the ovary inhibits the action 

 of infundibulin, pineal gland, corpus luteum and thymus upon the 

 secretion of the mammary gland. Pancreas, spleen, iodothyrin- 

 parathyroid and adrenalin also inhibit the action of indundibulin. 

 Orchitic extract increases the activity of infundibulin, thus being 

 a synergistic agent. Egg albumen does not inhibit the action of 

 infundibulin. 



