Protein Concentration and Absorption of Antibodies. 83 



54 (75o) 



The pancreatic lipase of infants in acute intestinal disturbances. 

 By Alfred F. Hess. 



[Research Laboratory, Dept. of Health, N. Y. C] 



In the former communication which considered the pancreatic 

 secretions in chronic malnutrition in infants, it was found that 

 various ferments of the gland are normally secreted even in 

 advanced instances of marasmus or atrophy. In the present 

 study of an acute disease, of acute intestinal indigestion or ali- 

 mentary intoxication, which was carried out also by the direct 

 method, by the use of the duodenal catheter the lipase was found 

 deficient, although the two other pancreatic ferments were present 

 in considerable amount. The deficiency of lipase seemed to some 

 degree characteristic of this disturbance; it is not a general char- 

 acteristic of all febrile conditions and was not met with in pneu- 

 monia or empyema. It is possible that the lack of lipolytic 

 activity in this disease should be correlated with the clinical 

 manifestation of fat intolerance, and the metabolic studies showing 

 a deficient absorption of fat. 



55 (75i) 



The influence of protein concentration upon the absorption of 

 antibodies from the subcutaneous tissues. 



By W. H. Park, L. W. Famulener and E. J. Banzhaf. 



[From the Laboratories of the Department of Health, New York City.] 



The experiments so far completed indicate that the concen- 

 tration of protein up to double its normal amount in an antitoxic 

 or agglutinating serum or globulin solution has but little influence 

 upon the absorption of the contained antitoxin or agglutinin 

 from the subcutaneous tissues of man or animals unless the 

 increased concentration of protein together with other substances 

 gives rise to a greater local inflammatory reaction. The absorp- 

 tion of agglutinin was markedly less in a number of rabbits in 

 which the subcutaneous injections of the high proteid solutions 

 were followed by infiltration and necrosis of the adjacent tissues. 



