96 



Scientific Proceedings (52). 



animals bile appeared in the urine on the second day after re- 

 covery from the anesthetic and persisted for two days. 



The anesthesia is complete for from ten to eighteen hours. 

 Three animals have failed to recover. 



When Grehant's anesthetic is given to full-grown dogs in half 

 the strength usually employed the output of urine is usually but 

 slightly diminished, the animals however become glycosuric, the 

 percentage of glucose having varied between .101-.301 per cent. 

 The urine does not contain acetone. 



Albumen is present with hyaline or hyaline and granular casts. 



The anesthesia is imperfect. Recovery is usually complete 

 within twelve hours. 



In a final series of animals, puppies were used. The age of 

 these animals ranged from six weeks to four and a half months. 

 Grehant's anesthetic was given in full strength. The animals 

 were completely anesthetized for two and a half to nine hours. 

 The output of urine was decidedly decreased and showed both 

 glucose and albumen. The percentage of glucose varied from 

 .0701-.202 per cent. Acetone was present in the urine of the 

 animal four and a half months old. All of the animals recovered. 



In the experiments conducted with morphine-ether, only full- 

 grown animals have so far been employed. The anesthetic was 

 given in sufficient quantity to keep the animal completely anes- 

 thetized for three hours. All of the animals recovered. The 

 recovery has been usually complete within six to eight hours. 



The output of urine in the twenty-four hours following the 

 anesthetic has been but slightly reduced, excepting in one animal 

 that was very old. In this animal the urine was reduced from 

 515 c.c. on the day prior to the anesthetic to 320 c.c. in the twenty- 

 four hour period following the anesthetic. The urine of this dog 

 showed a fairly heavy precipitate of albumen and .104 per cent, 

 of glucose. Acetone was not present. 



The remaining animals of this series have not developed a 

 glycosuria, and the urine has been free from acetone, albumen, and 

 casts. 



Experiments will be continued to ascertain if there exists any 

 relation between the age of the animal and the duration of the 

 anesthesia, and between the duration of the anesthesia and the 

 appearance of various abnormal constituents in the urine. 



