176 



Scientific Proceedings (54). 



sideration would seem justified. In these series we have made 

 use of white mice, having by preliminary observations determined 

 that a diet made up on the basis of Mendel and Osborne's work, of 

 a combination of glutenin and gliadin, would effectively retard the 

 growth of young white mice. One series of fifty mice inoculated 

 with the tumor obtained through the courtesy of Dr. Rous, of the 

 Rockefeller Institute, gave twenty-three tumors out of twenty-five 

 mice on a normal control diet, but only four out of twenty-five 

 on a vegetable protein diet, of which three tumors later dis- 

 appeared. In another series of fifty males, all again inoculated 

 with the same tumor, eighteen out of twenty-five on normal diet 

 developed tumors, with three out of twenty-five on a vegetable 

 protein diet; a third series of fifty females gave fifteen tumors out 

 of twenty-five on normal diet with seven out of twenty-five on a 

 vegetable protein diet. Expressed in percentage, 75 per cent, of 

 seventy-five mice developed a tumor under normal conditions; 

 19 per cent, of seventy-five mice developed a tumor when fed on 

 a vegetable protein diet, and further the tumors in the latter 

 series at thirty days were hardly larger than the tumors in the 

 normal fed mice at ten days. 



By referring to the work of Mendel and Osborne it will be 

 seen that it is not a question of starvation in the ordinary sense 

 of the word nor of anemia, but that the most probable conclusion 

 is that the tumor cell is subject to the same laws of growth as is 

 the normal somatic cell. 



in (807) 



On the inhibitory action cf certain anilin dyes upon bacterial 



development. 



By Charles E. Simon, B.A., M.D., assisted by Martha A. 



Wood, M.D. 



The triamino triphenyl methanes possess a well-marked in- 

 hibitory power over the development of certain pathogenic 

 organisms, notably staphylococci, streptococci, pneumococci and 

 meningococci, besides the anthrax bacillus and actinomyces. 

 This is quite pronounced, even in a dilution of 1 : 100,000. The 

 common pathogenic bacilli are not affected by the dyes in question, 

 in this concentration. 



