Extra Systoles in Otherwise Normal Heart. 33 



were etherized cats. The infusion of the extracts was injected 

 by the jugular. The arterial tension was registered by a Hiirthle 

 manometer. The extracts increasing the size of the spleen beyond 

 normal were adrenalin, infundibulin, corpus luteum, thymus, 

 orchitic extract, parathyroid and iodothyrin. The extracts di- 

 minishing the splenic volume were ovary and pineal. The agent 

 causing large rhythmical contractions of the spleen was splenic 

 extract. 



19 (836) 



Metabolism studies in a case of myasthenia gravis. 



By Theodore Diller, M.D., and Jacob 

 Rosenbloom, M.D., Ph.D. 



[From the Wards of the St. Francis Hospital and the Biochemical 

 Laboratory of the Western Pennsylvania Hospital, 

 Pittsburgh, Pa.] 



In an eight-day metabolism study on an individual suffering 

 from myasthenia gravis, we have studied the nitrogen metabolism 

 and urinary nitrogen partition, the sulphur metabolism and 

 urinary sulphur partition, and the calcium, magnesium, phos- 

 phorus and fat metabolism. The creatinin, uric acid and neutral 

 sulphur excretions were markedly less than the normal. A con- 

 siderable loss of calcium was found. The addition of 300 grammes 

 of egg yolk to the diet caused a phosphorus retention, not accom- 

 panied by retention of either calcium or magnesium. The fat 

 metabolism was normal. 



20 (837) 



A case of interpolated extrasystoles in an otherwise normal 

 human heart, illustrated by electrocardiograms. 



By M. Dresbach and S. A. Munford. 



[From the Physiological Laboratory, Cornell University, 

 Ithaca, N. Y.] 



At the meeting of this Society on October 16, 1912, we pre- 

 sented a case of interpolated extrasystoles in an otherwise normal 



